Anti-BD2 (Hu) from Goat (Clone: pAb) – unconj.

501,00 

100 µg
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SKU: CYT-074402 Category: Tag:
  • Overview
    SKU CYT-074402
    Specificity

    Species Reactivity

    Host Species

    Isotype

    Clone

    Clonality (Mono-/Polyclonal)

    Application

    ,

    Conjugation

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    Search Code

    , ,

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  • Additional Product Information
    Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the b-defensins by the pairing of their three disulfide bonds. To date, six human b-defensins have been identified, BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. b-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The b-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and in some cases, a propeptide sequence. b-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.
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