Phospho-antibodies detect specifically phosphorylated target-proteins. Non-phosphorylated variations are not recognized. The reversible phosphorylation of proteins is a significant regulatory processes in cells. Transfer of phophate groups to amino acid residues via protein kinases either activates or deactivates the target-protein. Thus, the level of protein activity, such as triggering of a signaling cascade, can be determined with phospho-specific antibodies. In this section you find more than 2500 validated antibodies from well-known manufacturers. Among them 800 worldwide unique phosphorylated antibodies of Affinity Biosciences (information and product list for download). For control experiments we recommend antibodies that recognize an epitope regardless of a phosphate group. You can find them in our primary antibody product search.
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