BSH-7082-100 – Anti-Desmin (Hu) from Mouse (BS21) – unconj. – 100 µl

Art.-Nr.
BSH-7082-100

Specificity
Desmin (Muscle Cells)
Species Reactivity
Human
Host Species
Mouse
Isotype
IgG1
Clone
BS21
Clonality (Mono-/Polyclonal)
monoclonal
Application
Immunohistochemistry (frozen sections)
Immunohistochemistry (Paraffin-embedded Sections)
Immunohistochemistry (IHC)
Conjugation
unconjugated
Format
purified antibody
concentrate
in Tris (pH 7,2)
0,03% NaN3
Product line / Topic
immunohistochemistry
Optibodies
Intended Use
for In vitro Diagnostic Use
Temperature – Storage
2-8°C
Manufacturer / Brand
Nordic BioSite

Background

Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.

Immunohistochemical staining (IHC) with anti-Desmin (Muskel Zellmarker) Antibody (clone BS21) - Nordic BioSite

A

Immunohistochemical staining (IHC) with anti-Desmin (Muskel Zellmarker) Antibody (clone BS21) - Nordic BioSite

B

Immunohistochemical staining (IHC) with anti-Desmin (Muskel Zellmarker) Antibody (clone BS21) - Nordic BioSite

C

Desmin stained tissue sections. Desmin Optibody (Clone: BS21) offers similar staining pattern. Also muscular layers of the small arteries are stained (a). Muscles of fetal part of placenta are strongly stained without any background staining (b). Rhabdomyosarcoma was stained strongly with Optibody (c).

More Information

Quantity: 100 µl

Usual delivery time: 8 business days


258,00  plus VAT
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