BSH-7959-1 – Anti-SOX10 (Hu) from Mouse (BS7) – unconj. – 1 ml

Art.-Nr.
BSH-7959-1

Specificity
SOX10
Species Reactivity
Human
Host Species
Mouse
Isotype
N/A
Clone
BS7
Clonality (Mono-/Polyclonal)
monoclonal
Application
Immunohistochemistry (frozen sections)
Immunohistochemistry (Paraffin-embedded Sections)
Immunohistochemistry (IHC)
Conjugation
unconjugated
Format
purified antibody
concentrate
in Tris (pH 7,2)
0,03% NaN3
Product line / Topic
immunohistochemistry
Optibodies
Intended Use
for In vitro Diagnostic Use
Temperature – Storage
2-8°C
Manufacturer / Brand
Nordic BioSite

Background

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. SOX10 is important and sensitive marker of melanoma especially for spindle cell and desmoplastic melanomas and schwannian neoplasms.

Immunohistochemical staining (IHC) with anti-SOX10 Antibody (clone BS7) - Nordic BioSite

A

Immunohistochemical staining (IHC) with anti-SOX10 Antibody (clone BS7) - Nordic BioSite

B

Immunohistochemical staining (IHC) with anti-SOX10 Antibody (clone BS7) - Nordic BioSite

C

Myoepithelial cells of breast (A), neuronal cells of appendix (B) and melanoma (C) have stained with SOX10 (Clone: BS7) optibody using 1:200 dilution and pH9 tris-EDTA pretreatment. Myoepithelial cells and neuronal cells have strong nuclear label. Neoplastic melanoma cells stained strongly (C).

More Information
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BSH-7959-1 - Anti-SOX10 (Hu) from Mouse (BS7) - unconj. - 1 ml

Quantity: 1 ml

Usual delivery time: 8 business days


598,00  plus VAT
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