Anti-AMACR (p504s) (Hu) from Mouse (IHC504) – unconj.
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Overview
SKU AB-138176 Specificity Species Reactivity Immunogen Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections)
Conjugation Dilution Format < 0.1% NaN3, 1% BSA, concentrate, in Tris buffer (pH 7.3-7.7), ProteinA/G purified antibody
Intended Use Temperature - Storage Temperature - Transport Manufacturer / Brand Uniprot_ID Gene_ID Alias 2-methylacyl-CoA racemase, Alpha-Methylacyl Coenzyme A Racemase, Alpha-methylacyl-CoA racemase, AMACR, p504s, RACE
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Additional Product Information
p504s, also known as alpha-Methylacyl Coenzyme A Racemase (AMACR), is an enzyme localized in the peroxisome and mitochondria that functions in beta-oxidation of branched chain fatty acids, as well as bile synthesis. AMACR has been clinically indicated as a tissue biomarker for prostate cancer and colorectal cancer, as well as high-grade prostatic intraepithelial neoplasia, a precursor lesion of prostate cancer. p504s overexpression has also been detected in a number of other cancers including ovarian, breast, bladder, lung, and renal cell carcinomas, lymphoma, and melanoma.
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Images
Immunohistochemical staining of formalin-fixed and paraffin-embedded (FFPE) human prostate cancer tissue section using anti-p504s mouse monoclonal antibody (Clone IHC504).
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