Mouse TRAIL (rec. protein)-unconj.
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Overview
SKU CYT-075815 Species Protein Source Application Conjugation Maximum Absorption Maximum Emission Format Intended Use Product line / Topic Search Code Manufacturer / Brand -
Additional Product Information
TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain&rsquo, which activates the cell is apoptotic machinery. Recombinant murine TRAIL is a 174 amino acid polypeptide (20.0 kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL protein.
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