Anti-CD15 Ab-3 (Hu) from Mouse (Clone: MMA,LeuM1) – unconj. ABF
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Overview
SKU DLN-007048 Specificity CD15 (Le-x, Lewis X, alpha-(1,3)-fucosyltransferase 4 (fut4))
Ab Species Reactivity Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application Flow Cytometry, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections)
Conjugation Format Application Note Positive Control Product line / Topic Intended Use Temperature - Storage Search Code Manufacturer / Brand - Datasheets and Downloads
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Additional Product Information
3-fucosyl-N-acetyllactosamine (3-FAL) or CD15 or X-hapten plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. CD15 is also expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkins disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
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