Anti-EGFR Ab-5 (Hu) from Mouse (Clone: H11) – unconj.
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Overview
SKU DLN-008919 Specificity Ab Species Reactivity Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections), Immunoprecipitation, Western Blot
Conjugation Format Positive Control Product line / Topic Intended Use Temperature - Storage Search Code Manufacturer / Brand - Datasheets and Downloads
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Additional Product Information
EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
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