Anti-Cytokeratin 5 Ab-1 (Hu) from Mouse (Clone: XM26) – unconj.
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Overview
SKU DLN-014350 Specificity Ab Species Reactivity Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections)
Conjugation Format Positive Control Product line / Topic Intended Use Temperature - Storage Search Code Manufacturer / Brand - Datasheets and Downloads
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Additional Product Information
Twenty human keratins are divided into acidic (pI <5.7) and basic (pI >6.0) subfamilies. Members of the acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor identification. Point mutations in cytokeratin5 gene can cause various types of epidermolysis bullosa simplex. It is expressed in most epithelial and biphasic mesotheliomas.
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