Anti-AMACR (p504s) (Hu) aus Maus (IHC504) – unkonj.
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Übersicht
Artikelnummer AB-138176 Spezifität Spezies-Reaktivität Immunogen Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung ELISA (Enzyme Linked Immunosorbent Assay), Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe)
Konjugation Verdünnung Format < 0,1% NaN3, 1% BSA, in Tris Puffer (pH 7,3-7,7), Konzentrat, ProteinA/G-gereinigter Antikörper
Zweckbestimmung Temperatur - Lagerung Temperatur - Transport Hersteller / Marke Uniprot_ID Gene_ID Alias 2-methylacyl-CoA racemase, Alpha-Methylacyl Coenzyme A Racemase, Alpha-methylacyl-CoA racemase, AMACR, p504s, RACE
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Weitere Produktinformationen
p504s, also known as alpha-Methylacyl Coenzyme A Racemase (AMACR), is an enzyme localized in the peroxisome and mitochondria that functions in beta-oxidation of branched chain fatty acids, as well as bile synthesis. AMACR has been clinically indicated as a tissue biomarker for prostate cancer and colorectal cancer, as well as high-grade prostatic intraepithelial neoplasia, a precursor lesion of prostate cancer. p504s overexpression has also been detected in a number of other cancers including ovarian, breast, bladder, lung, and renal cell carcinomas, lymphoma, and melanoma.
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Bilder
Immunhistochemische Färbung formalinfixierter Paraffinschnitte (FFPE) von menschlichem Prostatakarzinom-Gewebe unter Verwendung des monoklonalen Anti-p504s Antikörpers (Klon IHC504).
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