Anti-p53 tumor suppressor (p53) (Hu) aus Maus (IHC053) – unkonj.
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Übersicht
Artikelnummer AB-138372 Spezifität Spezies-Reaktivität Immunogen Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung ELISA (Enzyme Linked Immunosorbent Assay), Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe), Western Blot
Konjugation Verdünnung Format < 0,1% NaN3, 1% BSA, in Tris Puffer (pH 7,3-7,7), Konzentrat, ProteinA/G-gereinigter Antikörper
Zweckbestimmung Temperatur - Lagerung Temperatur - Transport Hersteller / Marke Uniprot_ID Gene_ID Alias Antigen NY-CO-13, Cellular Tumor Antigen P53, LFS1, Li-Fraumeni Syndrome, P53, P53 Tumor Suppressor, TP53, Transformation related protein 53, TRP53, Tumor Protein, Tumor Protein p53, Tumor Suppressor P53
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Weitere Produktinformationen
p53, also known as Tumour Protein 53 or TP53, is a tumour suppressor and transcription factor that functions in a number of anti-cancer activities including DNA repair, cell-cycle arrest, and apoptosis in response to DNA damage or other stressors. Mutations in p53 are linked to a number of malignant tumours, including those of the breast, ovary, bladder, colon, lung, and melanoma. Anti-p53 staining has been used to detect intratubular germ cell neoplasia, and also to distinguish between uterine serous carcinoma and endometrioid carcinoma.
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Bilder
Immunhistochemische Färbung formalinfixierter Paraffinschnitte (FFPE) von menschlichem Kolonkarzinom-Gewebe unter Verwendung des monoklonalen Anti-p53 Antikörpers (Klon IHC053).
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