Anti-Thymidylate synthase (TYMS) (Hu) aus Maus (IHC697) – unkonj.
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Übersicht
Artikelnummer AB-138428 Spezifität Spezies-Reaktivität Immunogen Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung ELISA (Enzyme Linked Immunosorbent Assay), Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe)
Konjugation Verdünnung Format < 0,1% NaN3, 1% BSA, in Tris Puffer (pH 7,3-7,7), Konzentrat, ProteinA/G-gereinigter Antikörper
Zweckbestimmung Temperatur - Lagerung Temperatur - Transport Hersteller / Marke Uniprot_ID Gene_ID Alias - Datenblätter und Downloads
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Weitere Produktinformationen
Thymidylate Synthase (TS) is a crucial enzyme responsible for the synthesis of 2‘-deoxythymidine-5‘-monophosphate (dTMP) a precursor for thymidylate which is necessary for DNA replication and repair from 2‘-deoxyuridine-5‘-monophosphate (dUMP). In terms of cancer, TS is an important target for cancer treatment as the inhibition of TS and therefore nucleotide synthesis necessary for cell growth has shown to be a vital part for successful treatment against colorectal, pancreatic and breast cancers.
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Bilder
Immunhistochemische Färbung formalinfixierter Paraffinschnitte (FFPE) von menschlichem Tonsillen-Gewebe unter Verwendung des monoklonalen Anti-Thymidylate Synthase Antikörpers (Klon IHC697).
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