Anti-Cleaved Caspase-1 (Asp296) /P20 (Hu,Ms,Rt) aus Kaninchen (pAk) – unkonj.
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Übersicht
Artikelnummer AF4005-02 Spezifität Spezies-Reaktivität Immunogen Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung Immunhistochemie (Gefrierschnitte), Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe), Western Blot
Konjugation Verdünnung Immunhistochemie (IHC): 1:50 – 1:200, Western Blot (WB): 1:500 – 1:2.000
Format 0,02% NaN3, 150 mM NaCl, 1mg/ml Antikörper, 50% Glycerol, in PBS (pH 7,4), Peptid-affinitätsgereinigter Antikörper (aus Antiserum)
Zweckbestimmung Temperatur - Lagerung Temperatur - Transport Hersteller / Marke Uniprot_ID - Datenblätter und Downloads
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Weitere Produktinformationen
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive (PubMed:28314590).
Caspase 1 (p20,Cleaved-Asp296) Antibody detects endogenous levels of fragment of activated Caspase 1 resulting from cleavage adjacent to Asp296.
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