Anti-Phospho-ANXA2 (Tyr238) (Hu,Ms,Rt) aus Kaninchen (pAk) – unkonj.

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Übersicht
Artikelnummer AF7097-02 Spezifität Spezies-Reaktivität Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung ELISA (Enzyme Linked Immunosorbent Assay), Immunhistochemie (Gefrierschnitte), Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe), Western Blot
Konjugation Verdünnung Immunhistochemie (IHC): 1:50 – 1:200, Western Blot (WB): 1:500 – 1:2.000
Format 0,02% NaN3, 150 mM NaCl, 1mg/ml Antikörper, 50% Glycerol, affinitätsgereinigter Antikörper (aus Antiserum), gereinigt durch sequentielle Chromatographie an Phospho- und Nicht-Phospho-Peptid-Affinitätssäulen, in PBS without Mg2+ and Ca2+ (pH 7,4)
Zweckbestimmung Temperatur - Lagerung Temperatur - Transport Hersteller / Marke Uniprot_ID Alias Annexin 2, Annexin A2, Annexin II, ANX-A2, ANX2L4, ANXA2, CAL1H, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, LIP2, Lipocortin II, LPC2, LPC2D, P36, PAP-IV, Phospho-ANXA2 (Tyr238), Placental anticoagulant protein IV, Protein I
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Weitere Produktinformationen
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640).
Phospho-ANXA2 (Tyr238) Antibody detects endogenous levels of ANXA2 only when phosphorylated at Tyr238