Anti-Collagen Type I (COL1) (Rt) aus Kaninchen – unkonj.
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Voraussichtliche Lieferzeit: 6 Werktage
Artikelnummer CO20141-0.1 Spezifität Spezies-Reaktivität Immunogen Wirtsspezies Isotyp Klonalität (Mono-/Polyklonal) Anwendung Konjugation Format Produktlinie / Thema Zweckbestimmung Temperatur - Lagerung Hersteller / Marke Uniprot_ID Alias
Type I Collagen usually exists as a heterotrimer formed by alpha 1(I) and alpha 2(I) chains and is found in bone, cornea, skin and tendon. In foetal tissues also homotrimers of alpha-1(I) are found, but they are not constituents of normal adult tissues. Collagens consist of a family of highly specialized glycoproteins of which at least 16 genetically distinct types are known to date. The basal unit of a collagen molecule consists of a triple-helical structure formed by 3 alpha-chains. Predominant amino acids are glycine, proline and hydroxproline. Regularly also lysines and hydroxylysines occur, which are responsible for cross-linkage and glycosylation of the protein chains. Different composition of alpha-chains and different glycosylation contribute to the high variability of collagens in different tissues and organs. Rat collagen type I 100%, rat collagen II, III, IV and V <0.1%, rat elastin <0.1% ( RIA at 1:200 dilution). Affinity purified antibody lyophilized from phosphate buffered solution, no BSA and preservative added.