Anti-IFN-gamma (Ms,Ro) aus Kaninchen (Klon: pAk) – unkonj.
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Übersicht
Artikelnummer CYT-026688 Spezifität Spezies-Reaktivität Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung ELISA (Enzyme Linked Immunosorbent Assay), Inhibition/Neutralisation, Western Blot
Konjugation Format Produktlinie / Thema Zweckbestimmung Suchcode Hersteller / Marke -
Weitere Produktinformationen
IFN-g is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-g receptors are present in most immune cells, which respond to IFN-g signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-g signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-g stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-g species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-g is a 15.6 kDa protein containing 134 amino acid residues.
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