PDGF-AA (rekombinantes Protein)-unkonj.
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Übersicht
Artikelnummer CYT-026822 Spezies Protein Ursprung Anwendung ELISA (Enzyme Linked Immunosorbent Assay), Funktionelle Studien, Western Blot
Konjugation Maximale Anregung Maximale Emission Format Zweckbestimmung Produktlinie / Thema Suchcode Hersteller / Marke -
Weitere Produktinformationen
Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-b binding protein that contains multiple protease inhibitor structural domains. It is expressed primarily in the ovary, testis, and brain, and can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin-A. The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence, and multiple identifiable structural features, including a WAP domain, a follistatin/Kazal domain, an immunoglobulin domain, two tandem Kunitz domains, and a netrin domain. Recombinant human GASP-1 is a 542 amino acid protein that migrates at an apparent molecular weight of approximately 55-66 kDa by SDS-PAGE analysis under non-reducing conditions.
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