PDGF-AB (rekombinantes Protein)-unkonj.
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Übersicht
Artikelnummer CYT-026823 Spezies Protein Ursprung Anwendung ELISA (Enzyme Linked Immunosorbent Assay), Funktionelle Studien, Western Blot
Konjugation Maximale Anregung Maximale Emission Format Zweckbestimmung Produktlinie / Thema Suchcode Hersteller / Marke -
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The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36a (IL-1F6), b (IL-1F8) and g (IL-1F9). IL-36b is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36b signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36b also functions as an agonist of NF-kappaB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3. Recombinant human IL-36b is a 17.3 kDa protein containing 154 amino acid residues.
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