Anti-IL-33 (Hu) aus Kaninchen (Klon: pAk) – unkonj.

501,00 

100 µg

Voraussichtliche Lieferzeit: 6 Werktage

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Artikelnummer: CYT-075004 Kategorie: Schlagwort:
  • Übersicht
    Artikelnummer CYT-075004
    Spezifität

    Spezies-Reaktivität

    Wirtsspezies

    Isotyp

    Klon

    Klonalität (Mono-/Polyklonal)

    Anwendung

    ,

    Konjugation

    Zweckbestimmung

    Suchcode

    , ,

    Hersteller / Marke

  • Weitere Produktinformationen
    IL-33 is a proinflammatory protein that may also regulate gene transcription. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines and is constitutively expressed in smooth muscle and airway epithelia. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1alpha or IL-1 beta stimulation. Similar to IL-1, IL-33 can be cleaved in vitro by caspase-1, generating an N-terminal fragment that is slightly shorter than the C-terminal fragment. The N-terminal portion of full length IL-33 contains a predicted bipartite nuclear localization sequence and a homeodomain-like helix-turn-helix DNA binding domain.
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Tel.: +49 (0)89 3799666-6