Anti-VEGFR-3/FLT-4 (Hu) aus Kaninchen (Klon: pAk) – unkonj.

300,00 

200 µg

Voraussichtliche Lieferzeit: 6 Werktage

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Artikelnummer: CYT-075508 Kategorie: Schlagwort:
  • Übersicht
    Artikelnummer CYT-075508
    Spezifität

    Spezies-Reaktivität

    Wirtsspezies

    Isotyp

    Klon

    Klonalität (Mono-/Polyklonal)

    Anwendung

    Konjugation

    Zweckbestimmung

    Suchcode

    , ,

    Hersteller / Marke

  • Weitere Produktinformationen
    Receptor tyrosine Kinase VEGFR-3, also known as FLT4, together with VEGFR1 (FIT1) and VEGFR2 (KDR/Flk-1), are the receptors for vascular endothelial growth factors (VEGF). The VEGFR family belongs to the class II subfamily of receptor tyrosine kinases (RTKs), containing a large extracellular region which is composed of seven Ig-like domains (D1-D7), a single transmembrane (TM) helix and cytoplasmic region with a tyrosine kinase activity. In VEGFR-3, the fifth Ig homology domain is proteolytically cleaved which results in polypeptides remain linked by two disulfide bonds. VEGFR-3 is widely expressed on all endothelia cells in early embryogenesis, while, in adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. VEGF-C and VEGF-D activation of VEGFR-3 plays an important role in the formation of the lymphatic vessel system.
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Bestellung:
Tel.: +49 (0)89 3799666-6
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Tel.: +49 (0)89 3799666-6