Human PDGF-AB (rekombinantes Protein)-unkonj.

107,00 

5 µg

Voraussichtliche Lieferzeit: 6 Werktage

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Artikelnummer: CYT-075722 Kategorie: Schlagwort:
  • Übersicht
    Artikelnummer CYT-075722
    Spezies

    Protein

    Ursprung

    Anwendung

    Konjugation

    Maximale Anregung

    Maximale Emission

    Format

    Zweckbestimmung

    Produktlinie / Thema

    Suchcode

    , ,

    Hersteller / Marke

  • Weitere Produktinformationen
    PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet a-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-a and PDGFR-b. PDGFR-a is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-b interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-AB is a 25.5 kDa disulfide-linked dimer, consisting of one A chain and one B chains (234 total amino acids).
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Bestellung:
Tel.: +49 (0)89 3799666-6
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Tel.: +49 (0)89 3799666-6