Maus PIGF (rekombinantes Protein)-unkonj.
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Übersicht
Artikelnummer CYT-075734 Spezies Protein Ursprung Anwendung Konjugation Maximale Anregung Maximale Emission Format gereinigtes rekombinantes Protein aus Baculo/Insekten-Zellen
Zweckbestimmung Produktlinie / Thema Suchcode Hersteller / Marke -
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Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF-1, PlGF-2 and PlGF-3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF-2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF-2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.
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