Anti-MUC14 (Hu) aus Kaninchen – unkonj.
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Übersicht
Artikelnummer CYT-104426 Spezifität Spezies-Reaktivität Wirtsspezies Isotyp Klonalität (Mono-/Polyklonal) Anwendung Konjugation Format Anwendungshinweis Lyophilisat in Wasser (steril) rekonstituieren (Konz. 0,1-1 mg/ml)
Zweckbestimmung Temperatur - Lagerung Hersteller / Marke -
Weitere Produktinformationen
Endomucin (endothelial sialomucin, also Endomucin-1/2 and Mucin-14) is an 80 – 120 kDa glycoprotein member of the Endomucin family of proteins. It is expressed on endothelial cells and depending upon its glycosylation pattern, can serve as either a pro- or anti-adhesive molecule. Mouse Endomucin precursor is 261 amino acids in length. It is type I transmembrane protein that contains a 170 aa extracellular domain (ECD) (aa 21 – 190) and a 50 aa cytoplasmic region. Three splice variants exist in the ECD. One shows a deletion of aa 91 – 141, a second shows a one aa substitution for aa 91 – 129, and a third shows a one aa substitution for aa 129 – 142. Over aa 21 – 90, mouse Endomucin shares 60% and 30% aa identity with rat and human Endomucin, respectively.
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