Anti-VEGF-A (Ms) aus Kaninchen – Biotin
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Übersicht
Artikelnummer CYT-104619 Spezifität Spezies-Reaktivität Wirtsspezies Isotyp Klonalität (Mono-/Polyklonal) Anwendung Konjugation Format 0,02% NaN3, affinitätsgereinigt durch antigenspezifische Affinitätschromatographie, Lyophilisat
Anwendungshinweis Lyophilisat in Wasser (steril) rekonstituieren (Konz. 0,1-1 mg/ml)
Produktlinie / Thema Zweckbestimmung Temperatur - Lagerung Hersteller / Marke -
Weitere Produktinformationen
Mouse VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors, fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant murine VEGF (isoform 164) is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 164 amino acid polypeptide chains.
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