Anti-VEGF-R2 (KDR, Flk-1) (Hu) aus Maus (EIC) – FITC
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Übersicht
Artikelnummer CYT-104633 Spezifität Spezies-Reaktivität Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung Konjugation Maximale Anregung Maximale Emission Format 0,02% NaN3, 1% BSA, flüssig, ProteinG-gereinigter Antikörper
Produktlinie / Thema Zweckbestimmung Temperatur - Lagerung Hersteller / Marke -
Weitere Produktinformationen
VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
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