Anti-TIMP-2 Ab-5 (Hu,Ms,Rt,Rb,Bo,Gp,Ro) aus Maus (Klon: 3A4) – unkonj.
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Übersicht
Artikelnummer DLN-007908 Spezifität Ab Spezies-Reaktivität Human, Kaninchen, Maus, Meerschweinchen, Nagetiere, Ratte, Rind
Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe), Western Blot
Konjugation Format Positivkontrolle Produktlinie / Thema Zweckbestimmung Temperatur - Lagerung Suchcode Hersteller / Marke - Datenblätter und Downloads
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Weitere Produktinformationen
TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
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