Anti-c-erbB-2 Ab-8 (Hu,Ms,Rt,Ro) aus Maus (Klon: e2-4001) – Biotin
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Übersicht
Artikelnummer DLN-008958 Spezifität Ab Spezies-Reaktivität Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung Konjugation Format Positivkontrolle Produktlinie / Thema Cytokine, Wachstumsfaktoren & Rezeptoren, Tumormarker/-biologie
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Weitere Produktinformationen
c-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein. The c-erbB-2 protein is overexpressed in a variety of carcinomas especially those of breast and ovary.
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