Anti-CA19-9 Ab-1 (Hu) aus Maus (Klon: 121SLE) – unkonj. ABF
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Übersicht
Artikelnummer DLN-009187 Spezifität Ab Spezies-Reaktivität Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung Konjugation Format Anwendungshinweis Positivkontrolle Produktlinie / Thema Zweckbestimmung Temperatur - Lagerung Suchcode Hersteller / Marke Alias CA 19-9, CA19-9, Carbohydrate antigen19-9, Ovarian tumor antigen, Pancreatic tumor antigen, Sialyl-Lewis a
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Weitere Produktinformationen
Mucin glycoprotein is a sialyl Lewis^a^ structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewis^a^ and/or Lewis^b^ blood group antigens. In normal tissues, sialyl Lewis^a^ antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings.
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