Anti-XRCC1 Ab-1 (Hu,Rt,Ro) aus Maus (Klon: 33-2-5) – unkonj.
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Übersicht
Artikelnummer DLN-009438 Spezifität Ab Spezies-Reaktivität Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe), Immunpräzipitation, Western Blot
Konjugation Format Positivkontrolle Produktlinie / Thema Zweckbestimmung Temperatur - Lagerung Suchcode Hersteller / Marke -
Weitere Produktinformationen
X-Ray Repair Cross Complementing (XRCC1) plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase beta through the N-terminal half. In testis XRCC1 is expressed at high levels. Cells with a mutation of this gene exhibit decreased single strand break repair and reduced recombination repair. They show increased double strand breaks, and sister chromatid exchange is increased up to 10-fold. The XRCC1 might serve as a scaffold protein during base excision-repair.
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