Anti-ÖR Ab-17 (Hu,Rt,Ms,Rb,Sh,Sw,Bo,Ro) aus Kaninchen (Klon: pAk) – unkonj.
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Übersicht
Artikelnummer DLN-012416 Spezifität Ab Spezies-Reaktivität Human, Kaninchen, Maus, Nagetiere, Ratte, Rind, Schaf, Schwein
Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe), Immunpräzipitation, Western Blot
Konjugation Format Peptid Positivkontrolle Produktlinie / Thema Marker-Moleküle, Steroide, Hormone, Wachstumsfaktoren & Rezeptoren, Transkription, Transkriptionsregulation, Tumormarker/-biologie
Zweckbestimmung Temperatur - Lagerung Suchcode Hersteller / Marke - Datenblätter und Downloads
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Weitere Produktinformationen
ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy
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