Anti-Cytokeratin 5 Ab-1 (Hu) aus Maus (Klon: XM26) – unkonj. IHC-RTU
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Übersicht
Artikelnummer DLN-014349 Spezifität Ab Spezies-Reaktivität Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung Konjugation Format Anwendungshinweis Positivkontrolle Produktlinie / Thema Zweckbestimmung Temperatur - Lagerung Suchcode Hersteller / Marke - Datenblätter und Downloads
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Weitere Produktinformationen
Twenty human keratins are divided into acidic (pI <5.7) and basic (pI >6.0) subfamilies. Members of the acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor identification. Point mutations in cytokeratin5 gene can cause various types of epidermolysis bullosa simplex. It is expressed in most epithelial and biphasic mesotheliomas.
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