Cluster of Differentiation 30 (CD30) ELISA Kit (Human), RUO (96 Tests)
exkl. MwSt. zzgl. Lieferkosten
Voraussichtliche Lieferzeit: 8 Werktage
Artikelnummer KBB-824 Artikelgruppe Artikelbezeichnung Spezies-Reaktivität Spezifität Probenmaterial Zweckbestimmung Temperatur - Lagerung Packungsgröße Hersteller / Marke Alias
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CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. This gene is mapped to 1p36.22. CD30 is expressed in embryonal carcinoma but not in seminoma and is thus a useful marker in distinguishing between these germ cell tumors. CD30 mast cell activation represents an IgE-independent activation pathway, which is important for understanding cutaneous inflammation associated with mast cells. In addition to those, CD30 is also associated with anaplastic large cell lymphoma.