Anti-ACTH (Rt,Hu) aus Maus (57) – unkonj.

388,00 

100 µg

Voraussichtliche Lieferzeit: 10 Werktage

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Artikelnummer: RA0266-C.5 Kategorien: , Schlagwörter: ,
  • Übersicht
    Artikelnummer RA0266-C.5
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  • Weitere Produktinformationen
    ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This antibody is specific to Synacthen (aa 1-24 of ACTH), This antibody does not react with CLIP (aa 17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific, posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin, and Met-enkephalin. ACTH is also produced by cells of the immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and in the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
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Tel.: +49 (0)89 3799666-6
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Tel.: +49 (0)89 3799666-6