Anti-alpha Tubulin (viele) aus Maus (TU-16) – unkonj.

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha- and beta-tubulin. This antibody recognizes an epitope of alpha-tubulin. The alpha-tubulin is a globular protein that exists in cells either as part of the soluble alpha/beta-tubulin dimer or polymerized into microtubules. In different species, it is coded by multiple tubulin genes that form tubulin classes (6 genes in human). Expressed tubulin genes are named tubulin isotypes. Some of the tubulin isotypes are expressed ubiquitously, while some have more restricted tissue expression. Alpha-tubulin is also subject to numerous post-translational modifications. Tubulin isotypes and their posttranslational modifications are responsible for multiple tubulin charge variants, or tubulin isoforms. Heterogeneity of alpha-tubulin is concentrated in the C-terminal structural domain.