Anti-Moesin (Hu) aus Maus (MSN491) – unkonj.
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Übersicht
Artikelnummer RA0211-C.5 Spezifität Spezies-Reaktivität Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung Immunhistochemie (Gefrierschnitte), Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe)
Konjugation Format Zweckbestimmung Temperatur - Lagerung Hersteller / Marke -
Weitere Produktinformationen
This antibody recognizes the 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophage, lymphocyte, fibroblastic, endothelial, epithelial, and neuronal cell lines, but not in blood cells. The ERM proteins (ezrin, radixin, and moesin) are involved in a variety of cellular functions such as cell adhesion, migration, and the organization of cell surface structures. They are highly homologous both in protein sequence and in functional activity with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin, whereas cells of endothelial and lymphoid origin express moesin.
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