Anti-Myeloide Zellen (Hu) aus Maus (BM-1) – unkonj.
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Übersicht
Artikelnummer RA0400-C.5 Spezifität Spezies-Reaktivität Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung Gel Supershift Assay, Immuncytochemie, Immunhistochemie (Gefrierschnitte), Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe), Western Blot
Konjugation Format Zweckbestimmung Temperatur - Lagerung Hersteller / Marke -
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Recognizes a 183kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. Clone BM-1 reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. BM-1 and BM-2 antibodies react with early precursor and mature forms of human myeloid cells. Clone BM-1 is useful in the identification of myelogenous leukemias, the distinction of granulocytic sarcomas from lymphoid malignancies, and the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells.
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