Anti-MUC1 (Mucin-1) / EMA (Hu) aus Maus (IHC623) – unkonj.
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Übersicht
Artikelnummer AB-138344 Spezifität Spezies-Reaktivität Immunogen Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung ELISA (Enzyme Linked Immunosorbent Assay), Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe)
Konjugation Verdünnung Format < 0,1% NaN3, 1% BSA, in Tris Puffer (pH 7,3-7,7), Konzentrat, ProteinA/G-gereinigter Antikörper
Zweckbestimmung Temperatur - Lagerung Temperatur - Transport Hersteller / Marke Uniprot_ID Gene_ID Alias CA153, Cancer antigen 15-3, Carcinoma-associated mucin, CD227, EMA, Episialin, H23AG, KL-6, MUC1, Mucin 1, Mucin-1, Peanut-reactive urinary mucin, PEM, Polymorphic epithelial mucin, PUM
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Weitere Produktinformationen
Mucin 1 (MUC1) is a membrane-bound glycoprotein involved in a number of protective and cell-signaling functions, including cell-cell adhesion, proliferation, motility, invasion, and survival. Overexpression of MUC1 is clinically indicated in breast carcinomas, papillary thyroid carcinomas, and thymic carcinomas, and reports have named MUC1 as a useful marker for differentiating thymic carcinoma from type B3 thymoma. The expression of MUC1 is correlated with the grade of malignancy in thymic epithelial tumours, and loss of MUC1 expression has been associated with reactive gastropathy. MUC1 is not expressed in normal human epidermis, but it has been detected in the epidermis of psoriatic plaques of biopsies from patients diagnosed with psoriasis vulgaris.
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Bilder
Immunhistochemische Färbung formalinfixierter Paraffinschnitte (FFPE) von menschlichem Brustkrebs-Gewebe unter Verwendung des monoklonalen Anti-MUC1 Antikörpers (Klon IHC623).
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