Anti-CD45R (B220) (Hu) aus Maus (IHC536) – unkonj.
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Übersicht
Artikelnummer AB-179487 Spezifität Spezies-Reaktivität Immunogen Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung ELISA (Enzyme Linked Immunosorbent Assay), Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe)
Konjugation Verdünnung Format < 0,1% NaN3, 1% BSA, in Tris Puffer (pH 7,3-7,7), Konzentrat, ProteinA/G-gereinigter Antikörper
Zweckbestimmung Temperatur - Lagerung Temperatur - Transport Hersteller / Marke Uniprot_ID Gene_ID Alias B220, CD45, CD45RA, Cluster of Differentiation 45, L-CA, LCA, Leukocyte Common Antigen, Ly-5, LY5, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200
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Weitere Produktinformationen
CD45R, also known as MB1, is an isoform of CD45 that is a member of the protein tyrosine phosphatase (PTPase) family. CD45R is expressed specifically on the surface of hematopoietic cells, and has demonstrated function as a regulator of the antigen and cytokine receptor signalling of B and T cells. Given that the antigen is located in the membrane of all B cells, with the exception of plasma cells and some mature T cells, Anti-CD45R exhibits specific reactivity with most B lymphocytes. The use of Anti-CD45R is primarily useful in distinguishing B cell lymphomas from T cell lymphomas, with specific reactivity to follicle center cells, mantle cells, some medullary thymocytes, and 80% of B cell lymphomas.
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Bilder
Immunhistochemische Färbung formalinfixierter Paraffinschnitte (FFPE) von menschlichem Tonsillen-Gewebe unter Verwendung des monoklonalen Anti-CD45R (B220) Antikörpers (Klon IHC536).
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