Anti-T-cell Immunoglobulin Mucin-3 (TIM-3) (Hu) aus Maus (IHC003) – unkonj.
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Artikelnummer AB-138422 Spezifität Spezies-Reaktivität Immunogen Wirtsspezies Isotyp Klon Klonalität (Mono-/Polyklonal) Anwendung ELISA (Enzyme Linked Immunosorbent Assay), Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe)
Konjugation Verdünnung Format < 0,1% NaN3, 1% BSA, in Tris Puffer (pH 7,3-7,7), Konzentrat, ProteinA/G-gereinigter Antikörper
Zweckbestimmung Temperatur - Lagerung Temperatur - Transport Hersteller / Marke Uniprot_ID Gene_ID Alias CD366, HAVcr-2, HAVCR2, Hepatitis A virus cellular receptor 2, KIM-3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell Immunoglobulin Mucin-3, T-cell membrane protein 3, TIM-3, TIM3, TIMD-3, TIMD3
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T-Cell Immunoglobulin and Mucin-Domain-Containing Molecule-3 (TIM3) is present on T-helper type 1 lymphocytes and other immune cells, including dendritic cells and natural killer cells. TIM3 is overexpressed in CD4+ tumour-infiltrating lymphocytes, including those with non-small cell lung cancer associated with poor prognoses. TIM3 has recently emerged as a potential target for cancer immunotherapy.
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