Anti-T-Cell Immunoglobulin Mucin-3 (TIM-3) (Hu) from Mouse (IHC003) – unconj.
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Overview
SKU AB-138422 Specificity Species Reactivity Immunogen Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections)
Conjugation Dilution Format < 0.1% NaN3, 1% BSA, concentrate, in Tris buffer (pH 7.3-7.7), ProteinA/G purified antibody
Intended Use Temperature - Storage Temperature - Transport Manufacturer / Brand Uniprot_ID Gene_ID Alias CD366, HAVcr-2, HAVCR2, Hepatitis A virus cellular receptor 2, KIM-3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell Immunoglobulin Mucin-3, T-cell membrane protein 3, TIM-3, TIM3, TIMD-3, TIMD3
- Datasheets and Downloads
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Additional Product Information
T-Cell Immunoglobulin and Mucin-Domain-Containing Molecule-3 (TIM3) is present on T-helper type 1 lymphocytes and other immune cells, including dendritic cells and natural killer cells. TIM3 is overexpressed in CD4+ tumour-infiltrating lymphocytes, including those with non-small cell lung cancer associated with poor prognoses. TIM3 has recently emerged as a potential target for cancer immunotherapy.
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Images
Immunohistochemical staining of formalin-fixed and paraffin-embedded (FFPE) human kidney tissue section using anti-TIM3 mouse monoclonal antibody (Clone IHC003).
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