Anti-Mouse CD3 antibody for formalin-fixed and paraffin-embedded tissue

You have the choice: Rat clone HH3E or Rabbit monoclonal antibody.

Rat monoclonal antibody HH3E and our purified Rabbit polyclonal antibody have been specifically validated for the detection of murine CD3 in formalin-fixed paraffin-embedded tissue sections (mouse FFPE). CD3 is a defining feature of cells belonging to the T cell lineage and can therefore be used as T cell marker. During T cell maturation the expression of CD3 migrates from the cytoplasm of pro-thymocytes to the cell-membrane of thymocytes.

The specific appearance at all stages of T cell development make CD3 an ideal marker for normal T cells and T cell neoplasms (lymphomas, leukemias). Moreover, CD3 is a usefull immunohistochemical marker for T cells in tissue sections.

Liver
Spleen

Immunhistochemistry of mouse CD3e with purified Rabbit polyclonal antibody in standard-FFPE tissue sections.
(All sections were stained by ABC method with HRP according to standard procedures. Pictures courtesy of Christel Bonnas, Synaptic Systems, Göttingen, Germany)

Milz2
Spleen
Lymp-node-B_CD3
Lymph node
Kidney-D_CD3
Kidney

Immunhistochemistry of mouse CD3e with Rat clone HH3E in standard-FFPE tissue sections.
(All sections were stained by an indirect alkaline phosphatase method according to standard procedures and counterstaining with Hämatoxylin. Pictures courtesy of Prof.H.Stein, Pathodiagnostik Berlin, Berlin, Germany)

Order: anti-msCD3 FFPE / mono- & polyclonal

Validated for the detection of CD3 in mouse FFPE-tissue sections.

>> Order Rt clone HH3E

>> Order Rb polyclonal

IHC Antibodies – Mouse Histology

IHC-validated marker for Mouse Histology – Specifically developed for murine formalin-fixed and paraffin-embedded tissue (FFPE)!

Antibodies for Mouse Histology