Anti-Immunoglobulin G kappa (IgG kappa) (Hu) from Mouse (IHC610) – unconj.
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Overview
SKU AB-138321 Specificity Species Reactivity Immunogen Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections), Western Blot
Conjugation Dilution Format < 0.1% NaN3, 1% BSA, concentrate, in Tris buffer (pH 7.3-7.7), ProteinA/G purified antibody
Intended Use Temperature - Storage Temperature - Transport Manufacturer / Brand Uniprot_ID Gene_ID Alias Ig kappa chain C region, IGKC, IGKCD, Immunoglobulin kappa constant, Immunoglobulin kappa light chain
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Additional Product Information
Anti-Kappa recognizes surface immunoglobulin on normal and neoplastic B-cells, and has been indicated as a potential aid in the identification of leukemias, plasmacytomas, and certain non-Hodgkin‘s lymphomas, where the expression of a single light chain class is restricted. The determination of light chain ratio is critical in evaluating B-cell neoplasms, as the majority of B-cell lymphomas express either kappa or lambda light chains, while a mixture of kappa and lambda is characteristic of reactive proliferations. In paraffin-embedded tissue, Anti-Kappa displays strong staining of kappa-positive plasma cells, as well as cells that have absorbed exogenous immunoglobulins.
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Images
Immunohistochemical staining of formalin-fixed and paraffin-embedded (FFPE) human ovary tissue section using anti-Kappa mouse monoclonal antibody (Clone IHC610).
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