Anti-Myogenin (MYOG) (Hu) from Mouse (IHC631) – unconj.
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Overview
SKU AB-138360 Specificity Species Reactivity Immunogen Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections)
Conjugation Dilution Format < 0.1% NaN3, 1% BSA, concentrate, in Tris buffer (pH 7.3-7.7), ProteinA/G purified antibody
Intended Use Temperature - Storage Temperature - Transport Manufacturer / Brand Uniprot_ID Gene_ID Alias bHLHc3, Class C basic helix-loop-helix protein 3, MYF4, MYOG, Myogenic Factor 4, Myogenin
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Additional Product Information
Myogenin belongs to a family of myogenic transcription factors, including MyoD, Myf5, and MRF4, which are critical in muscle development. Myogenin is found strictly in cells of skeletal muscle origin, and is therefore used as a biomarker for tumours of the muscle lineage, including alveolar rhabdomyosarcomas. Anti-Myogenin staining may occur in Wilms‘ tumour, and it labels the nuclei of myoblasts in developing muscle tissue. It is also expressed in some leiomyosarcomas.
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Images
Immunohistochemical staining of formalin-fixed and paraffin-embedded (FFPE) human rhabdomysarcoma tissue section using anti-Myogenin mouse monoclonal antibody (Clone IHC631).
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