Anti-Prosaposin (PSAP) (Hu) from Mouse (IHC655) – unconj.
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Overview
SKU AB-138396 Specificity Species Reactivity Immunogen Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections)
Conjugation Dilution Format < 0.1% NaN3, 1% BSA, concentrate, in Tris buffer (pH 7.3-7.7), ProteinA/G purified antibody
Intended Use Temperature - Storage Temperature - Transport Manufacturer / Brand Uniprot_ID Gene_ID Alias Cerebroside sulfate activator, CSAct, Dispersin, GLBA, Glucosylceramidase activator, Pro-Saposin, Proactivator Polypeptide, Prosaposin, PSAP, SAP1, Sphingolipid Activator 1, Sulfatide/GM1 activator
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Additional Product Information
Prostatic Specific Acid Phosphatase (PSAP) is a prostatic enzyme found in the glandular epithelium of the prostate. PSAP levels are elevated in hyperplastic prostate and prostate carcinoma, with the highest levels being detected in metastasized prostate cancer. Moderate overexpression of PSAP is also characteristic of diseases of the bone (such as Paget‘s disease or hyperparathyroidism), diseases of blood cells (such as sickle-cell disease), multiple myeloma, or lysosomal storage diseases (such as Gaucher‘s disease). PSAP is considered more sensitive, yet less specific, than PSA, however Anti-PSAP can act as a useful complement to Anti-PSA under suitable clinical contexts.
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Images
Immunohistochemical staining of formalin-fixed and paraffin-embedded (FFPE) human prostate tissue section using anti-PSAP mouse monoclonal antibody (Clone IHC655).
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