Anti-Transcription factor E3 (TFE3) (Hu) from Mouse (IHC672) – unconj.
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Overview
SKU AB-138434 Specificity Species Reactivity Immunogen Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections), Western Blot
Conjugation Dilution Format < 0.1% NaN3, 1% BSA, concentrate, in Tris buffer (pH 7.3-7.7), ProteinA/G purified antibody
Intended Use Temperature - Storage Temperature - Transport Manufacturer / Brand Uniprot_ID Gene_ID Alias bHLHE33, Class E basic helix-loop-helix protein 33, TFE3, Transcription factor E3
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Additional Product Information
Transcription Factor E3 (TFE3) is a transcription factor that binds to the MUE3-type E-box sequences involved in TGF-beta signaling. Anti-TFE3 staining is the most sensitive and specific indicator of Xp11 translocation renal cell carcinomas. Since alveolar soft part sarcoma (ASPS) is characterized by a specific chromosomal rearrangement resulting in a chimeric transcription factor (ASPSCR1-TFE3), this TFE3 IVD antibody is also a useful diagnostic tool for recognizing ASPS.
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Images
Immunohistochemical staining of formalin-fixed and paraffin-embedded (FFPE) human kidney tissue section using anti-TFE3 mouse monoclonal antibody (Clone IHC672).
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