Anti-p63 (TP63) (Hu) from Mouse (IHC063) – unconj.
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Overview
SKU AB-179515 Specificity Species Reactivity Immunogen Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections)
Conjugation Dilution Format < 0.1% NaN3, 1% BSA, concentrate, in Tris buffer (pH 7.3-7.7), ProteinA/G purified antibody
Intended Use Temperature - Storage Temperature - Transport Manufacturer / Brand Uniprot_ID Gene_ID Alias Chronic ulcerative stomatitis protein, CUSP, EEC3, Keratinocyte transcription factor, KET, LMS, OFC8, P63, RHS, SHFM4, TP53CP, TP63, TP73L, Tumor Protein p53-Competing Protein, Tumor Protein p63
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Additional Product Information
p63 is a tumor suppressor protein that is very similar to p53 in structure and function, while being homologous to p73. p63 is important in development and differentiation, and has been identified as a useful marker for distinguishing between lung squamous cell carcinomas and adenocarcinomas. Anti-p63 is also used to differentiate between benign and malignant prostate and breast lesions, due to its labeling of the nuclei of myoepithelial cells in both tissue types.
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Images
Immunohistochemical staining of formalin-fixed and paraffin-embedded (FFPE) human prostate cancer tissue section using anti-p63 (TP63) mouse monoclonal antibody (Clone IHC063).
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