Anti-CDKN1C (p57 Kip2) (Hu) from Mouse (IHC057) – unconj.
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Overview
SKU AB-180258 Specificity Species Reactivity Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections)
Conjugation Dilution Format < 0.1% NaN3, 1% BSA, concentrate, in Tris buffer (pH 7.3-7.7), ProteinA/G purified antibody
Intended Use Temperature - Storage Temperature - Transport Manufacturer / Brand Uniprot_ID Gene_ID Alias - Datasheets and Downloads
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Additional Product Information
p57kip2, also known as p57, is a tumor suppressor protein that causes cell cycle arrest at G1 by binding G1 cyclin-CDK complexes. The p57kip2 gene is a potential tumor suppressor target as the gene is located in a chromosomal region implicated in sporadic cancers, Wilms‘ tumor, and Beckwith Wiedemann syndrome. Anti-p57kip2 labels many cytotrophoblast nuclei and stromal cells in normal placenta, and is useful in differentiating between complete hydatidiform mole and partial hydatidiform mole or hydropic abortion.
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Images
Immunohistochemical staining of formalin-fixed and paraffin-embedded (FFPE) human placenta tissue section using anti-p57 Kip2 (CDKN1C) mouse monoclonal antibody (Clone IHC057).
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