Anti-Thyroglobulin (Hu) from Mouse (JGN3) – unconj.
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Overview
SKU DIA-TGN-OD Specificity Species Reactivity Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections)
Conjugation Dilution Format < 0.1% NaN3, 1% BSA, concentrate, in Tris buffer (pH 7.3-7.7), ProteinA/G purified antibody
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Additional Product Information
Mouse monoclonal anti-Thyroglobulin antibody clone JGN3 is suitable for the immunohistological detection of Thyroglobulin in routine-fixed paraffin embedded tissue sections Thyroglobulin is present in the thyroid follicular cells. Thyroglobulin is a precursor of thyroid hormones and nearly all thyroid follicular carcinomas stain for thyroglobulin. Poorly differentiated carcinomas and non-thyroid adenocarcinomas do not stain for thyroglobulin. Anti-Thyroglobulin antibody clone JGN3 is a useful tool for identification of papillary and follicular thyroid carcinomas. Moreover, a panel of Anti-Thyroglobulin and Anti-Calcitonin is useful for identifying medullary thyroid carcinomas, whereas a panel of Anti-Thyroglobulin and Anti-TTF1 is useful for distinguishing between primary thyroid and lung neoplasms.
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Images
Thyroid adenoma with accumulation of throglobulin positive masses. Thyroglobulin negative anaplastic thyroid carcinoma. Follicular thyroid carcinoma with luminal throglobulin staining. Papillary thyroid carcinoma with mosaic-like cytoplasmic staining.
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