Anti-CD45RO (Hu,Ms,Rt,Rb,Dg,Ca,Sh,Sw,Mo,Bo,Ck,Ho) from Mouse (UCHL1 (WS IV)) – unconj.

This antibody recognizes a 180-185kDa protein, identified as an isoform of leukocyte common antigen (CD45RO) (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B-cells or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful in identifying T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.