Anti-Napsin A (Hu) from Rabbit (pAb) – unconj.

Napsin is a pepsin-like aspartic proteinase connected with the maturation of surfactant protein B. There are two closely related napsins: napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney, but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.